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Fetal and neonatal alloimmune thrombocytopenia: current trends in diagnosis and therapy.
- Source :
-
Transfusion medicine (Oxford, England) [Transfus Med] 1992 Dec; Vol. 2 (4), pp. 265-71. - Publication Year :
- 1992
-
Abstract
- Neonatal thrombocytopenia affects 20-40% of the infants in intensive care units. The frequency of neonatal alloimmune thrombocytopenia (NAIT) is estimated at 1/1500 to 1/5000 live births. The risk of morbidity is significant with 20% neurological sequelae and the death rate is estimated at 10% of affected infants. During recent years considerable efforts have been made to prevent fetal bleeding and to avoid birth trauma, which have significantly changed the natural history of NAIT.
- Subjects :
- Antigens, Human Platelet immunology
Blood Component Transfusion
Blood Platelets immunology
Blood Transfusion, Intrauterine
Female
Fetal Blood immunology
Fetal Diseases diagnosis
Fetal Diseases epidemiology
Fetal Diseases therapy
Hemorrhage prevention & control
Histocompatibility Testing
Humans
Incidence
Infant, Newborn
Platelet Count
Platelet Transfusion
Pregnancy
Pregnancy Outcome
Prenatal Diagnosis
Risk Factors
Thrombocytopenia diagnosis
Thrombocytopenia epidemiology
Thrombocytopenia immunology
Thrombocytopenia therapy
Treatment Outcome
Fetal Diseases immunology
Immunity, Maternally-Acquired
Isoantibodies immunology
Thrombocytopenia congenital
Subjects
Details
- Language :
- English
- ISSN :
- 0958-7578
- Volume :
- 2
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Transfusion medicine (Oxford, England)
- Publication Type :
- Academic Journal
- Accession number :
- 1339580
- Full Text :
- https://doi.org/10.1111/j.1365-3148.1992.tb00168.x