Topoisomerase-targeting antitumor drugs: mechanisms of cytotoxicity and resistance.

Authors :: Liu LF
D'Arpa P
Source :: Important advances in oncology [Important Adv Oncol] 1992, pp. 79-89.
Publication Year :: 1992

Subjects :: Animals
Camptothecin pharmacology
Cell Cycle drug effects
Cell Death drug effects
DNA Damage
DNA, Neoplasm metabolism
DNA, Superhelical metabolism
Drug Resistance
Gene Expression Regulation, Enzymologic
Humans
Tumor Cells, Cultured drug effects
Tumor Cells, Cultured enzymology
Antineoplastic Agents pharmacology
Topoisomerase I Inhibitors
Topoisomerase II Inhibitors

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