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Relapsing and remitting human immunodeficiency virus-associated leukoencephalomyelopathy.
- Source :
-
Annals of neurology [Ann Neurol] 1992 Jan; Vol. 31 (1), pp. 34-8. - Publication Year :
- 1992
-
Abstract
- We describe a 33-year-old homosexual man with a steroid-responsive, remitting and relapsing leukoencephalopathy associated with recent human immunodeficiency virus type 1 (HIV-1) seroconversion. Biopsy of a parieto-occipital lesion revealed demyelination and astrogliosis with focal necrosis. Detailed investigations demonstrated no pathogens in the brain other than HIV-1. This patient illustrates that a neurological disorder clinically indistinguishable from multiple sclerosis may be the presenting manifestation of HIV-1 infection and may occur in the absence of clinically significant immunosuppression.
- Subjects :
- AIDS Dementia Complex diagnosis
Adult
Bone Marrow microbiology
Brain microbiology
Brain pathology
Demyelinating Diseases diagnosis
Demyelinating Diseases pathology
Diagnosis, Differential
HIV-1 isolation & purification
Humans
JC Virus isolation & purification
Leukoencephalopathy, Progressive Multifocal diagnosis
Male
Multiple Sclerosis diagnosis
Recurrence
Demyelinating Diseases microbiology
HIV Infections complications
HIV-1 pathogenicity
Subjects
Details
- Language :
- English
- ISSN :
- 0364-5134
- Volume :
- 31
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Annals of neurology
- Publication Type :
- Academic Journal
- Accession number :
- 1311910
- Full Text :
- https://doi.org/10.1002/ana.410310107