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Thoracic organ transplants in the United States from October 1987 through December 1991: a report from the UNOS Scientific Registry for Organ Transplants.
- Source :
-
Clinical transplants [Clin Transpl] 1992, pp. 33-43. - Publication Year :
- 1992
-
Abstract
- 1. In 1991 there were 2,127 heart, 402 lung, and 51 heart-lung transplants performed in the United States. These numbers reflect increases of 27% for heart, over 1000% for lung, and a decrease of 31% for heart-lung transplants since 1988. 2. The number of programs performing heart transplants has increased by 16% since 1988, whereas the number of programs performing lung transplants has tripled over that time. 3. The most frequent primary indications for thoracic transplantation were: cardiomyopathy (45%) and coronary artery disease (41%) for heart; primary pulmonary hypertension (43%) and congenital/Eisenmenger's for heart-lung; and emphysema/chronic obstructive pulmonary disease (28%) and Alpha-1 antitrypsin deficiency (20%) for lung. 4. Average cold ischemic time increased gradually between 1988 and 1991: 2.7 hours for hearts transplanted in 1991 compared with 3.3 hours for heart-lungs, and 4.3 for lungs. 5. Between 1988 and December 1991, the following percentages increased significantly: pediatric heart and lung transplantations; non-White thoracic transplant recipients and donors; the use of thoracic organs from younger (< or = 5 yrs) as well as older (> or = 45 yrs) donors; and local utilization of thoracic organs. 6. For the entire period covered by this report, 1-year recipient survival rates were: heart 81.6%, heart-lung 55.4%, and lung 67.2%. Patient survival was significantly lower in heart retransplants or when the primary indication for transplantation was the treatment of congenital disease. Between 1988 and 1991, 1-year survival appeared to have increased significantly for heart-lung and lung recipients.
- Subjects :
- Adolescent
Adult
Aged
Child
Child, Preschool
Female
Graft Survival
Heart Transplantation mortality
Heart-Lung Transplantation mortality
Humans
Infant
Infant, Newborn
Lung Transplantation mortality
Male
Middle Aged
Survival Rate
Tissue Donors statistics & numerical data
United States epidemiology
Heart Transplantation statistics & numerical data
Heart-Lung Transplantation statistics & numerical data
Lung Transplantation statistics & numerical data
Registries
Subjects
Details
- Language :
- English
- ISSN :
- 0890-9016
- Database :
- MEDLINE
- Journal :
- Clinical transplants
- Publication Type :
- Academic Journal
- Accession number :
- 1306709