Analytical comparison of an enzyme-amperometric method for chlorocresol determination in ointments with colorimetry and liquid chromatography.

The direct determination of chlorocresol in n-hexane extracts of commercial ointments was successfully performed using an enzyme-amperometric probe for analysis of phenols and working in previously characterized and optimized non-aqueous solvents. The analytical data obtained were compared with those found by using classical HPLC or chemical spectrophotometric method for determination of phenols.