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Effect of thermal damage and biaxial loading on the optical properties of a collagenous tissue.
- Source :
-
Journal of biomechanical engineering [J Biomech Eng] 2003 Aug; Vol. 125 (4), pp. 540-8. - Publication Year :
- 2003
-
Abstract
- Thermal denaturation can induce marked changes in the optical and mechanical properties of collagenous tissues. The optical properties are important in both therapeutic and diagnostic applications of lasers in medicine. Although mechanical stress can be caused by collagen shrinkage in laser-based therapies, how the mechanical loading state affects the optical properties is not well understood. We used a new computer-controlled biaxial testing system to subject bovine epicardium to various loading conditions both before and after multiple levels of thermal damage. An integrating sphere technique was used to measure transmittance and diffuse reflectance, from which absorption and scattering coefficients were calculated using a Monte Carlo method. Results showed that the scattering coefficient increased with increasing mechanical load but decreased as the degree of thermal damage increased. There was no significant change in the absorption coefficient due to thermal damage over the ranges studied.
- Subjects :
- Animals
Burns etiology
Connective Tissue injuries
Connective Tissue physiopathology
Connective Tissue radiation effects
Culture Techniques instrumentation
Dose-Response Relationship, Radiation
Elasticity
Equipment Failure
Pericardium injuries
Photometry methods
Swine
Temperature
Burns physiopathology
Culture Techniques methods
Hot Temperature adverse effects
Pericardium physiopathology
Pericardium radiation effects
Photometry instrumentation
Tomography, Optical Coherence methods
Subjects
Details
- Language :
- English
- ISSN :
- 0148-0731
- Volume :
- 125
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of biomechanical engineering
- Publication Type :
- Academic Journal
- Accession number :
- 12968579
- Full Text :
- https://doi.org/10.1115/1.1591202