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Risk factors for cardiovascular disease in a Brazilian population-based cohort study.
- Source :
-
International journal of cardiology [Int J Cardiol] 2003 Aug; Vol. 90 (2-3), pp. 205-11. - Publication Year :
- 2003
-
Abstract
- Objective: Our aim was to investigate risk factors for cardiovascular disease (CVD) in a population-based Brazilian cohort.<br />Design and Methods: A cohort study was conducted with 1091 individuals identified through multi-stage probability sampling in Porto Alegre, Brazil. Risk factors were investigated among demographic and anthropometric characteristics, including education, smoking habits, income, alcoholic beverage consumption, and blood pressure. A fatal or non-fatal episode of myocardial infarction, stroke, or heart failure, and cases of sudden death comprised the composite endpoint.<br />Results: Vital status was determined in 982 (90.0%) of the participants of the original cohort after 6.0+/-1.7 years of follow-up. A total of 52 individuals presented a cardiovascular event. Male gender (hazard ratio (HR) 2.01, 95% CI 1.03-3.91), systolic blood pressure (mmHg) (HR 1.03, 95% CI 1.01-1.04) and alcohol consumption (g/day) (HR 1.001, 95% CI 1.00-1.003) were associated with the incidence of CVD after controlling for confounding. Body mass index (HR 1.05, 95% CI 0.99-1.11) and current or previous smoking (HR 1.65, 95% CI 0.83-3.26) showed a trend for a positive association.<br />Conclusions: We confirmed that male gender, systolic blood pressure, obesity and smoking are risk factors for cardiovascular disease in a Brazilian population. The positive association between alcohol consumption and incident CVD was unexpected and deserves replication.
- Subjects :
- Adult
Brazil epidemiology
Cohort Studies
Cross-Sectional Studies
Female
Humans
Hypertension complications
Incidence
Male
Middle Aged
Obesity complications
Proportional Hazards Models
Risk Factors
Sex Factors
Smoking adverse effects
Cardiovascular Diseases epidemiology
Cardiovascular Diseases etiology
Subjects
Details
- Language :
- English
- ISSN :
- 0167-5273
- Volume :
- 90
- Issue :
- 2-3
- Database :
- MEDLINE
- Journal :
- International journal of cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 12957753
- Full Text :
- https://doi.org/10.1016/s0167-5273(02)00556-9