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[Genetic analysis of wild measles virus strains isolated in the european part of the Russian Federation].

Authors :
Zhuravleva IuN
Lugovtsev VIu
Voronina OL
Shilov IA
Vaniusheva OV
Lunin VG
Naumova MA
Mamaeva TA
Tikhonova NT
Source :
Voprosy virusologii [Vopr Virusol] 2003 Jul-Aug; Vol. 48 (4), pp. 29-35.
Publication Year :
2003

Abstract

Eleven wild measles virus isolated, in 1988 and in 1999-2001 in the European territory of the Russian Federation, were investigated. On the basis of an analysis of N-gene region sequences, encoding the COOH terminal end of nucleoprotein, the isolates were divided into 2 subgroups. According to the WHO classification, subgroup 1 was in line with genotype A and subgroup 2--with genotype D. Subgroup 2 was close to genotype D4 but differed from it according to its composition of nucleotides on the average by 2.8%, and according to its amino-acid composition--by 2.6%. with respect to the WHO criteria, the latter can be referred to preliminarily as an independent genotype. Finally, the measles viruses' strains of genetic groups A and D circulated in the Russian Federation in 1988, and in 1999-2001.

Details

Language :
Russian
ISSN :
0507-4088
Volume :
48
Issue :
4
Database :
MEDLINE
Journal :
Voprosy virusologii
Publication Type :
Academic Journal
Accession number :
12945204