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[Arterial hypertension, its metabolic aspects and kidney function in patients after hemorrhagic fever with renal syndrome].

Authors :
Pimenov LT
Dudarev MV
Vasil'ev MIu
Source :
Terapevticheskii arkhiv [Ter Arkh] 2003; Vol. 75 (6), pp. 28-31.
Publication Year :
2003

Abstract

Aim: To characterize late convalescence after hemorrhagic fever with renal syndrome (HFRS), i.e. metabolic disorders and their relation with arterial pressure (AP) and renal function.<br />Material and Methods: 202 HFRS convalescents were followed up with measurements of AP, purin, carbohydrate and lipid metabolisms, study of glomerular and tubular dysfunctions.<br />Results: A stable rise of arterial pressure registered in 24% HFRS convalescents was associated with intraglomerular hypertension, affected concentration ability of the kidneys and tubular transport of beta 2-microglobulin in the presence of metabolic disorders: hyperuricemia, hyperinsulinemia and hyperlipidemia of type IIa. A significant correlation was found between arterial hypertension and renal dysfunction and metabolic disorders.<br />Conclusion: Late convalescence after HFRS is characterized by glomerular and tubular dysfunctions, persistent elevation of AP and hormonal-metabolic atherogenic and diabetogenic disturbances.

Details

Language :
Russian
ISSN :
0040-3660
Volume :
75
Issue :
6
Database :
MEDLINE
Journal :
Terapevticheskii arkhiv
Publication Type :
Academic Journal
Accession number :
12920955