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Implications of cigarette smoking for the management of patients with acute coronary syndromes.
- Source :
-
Progress in cardiovascular diseases [Prog Cardiovasc Dis] 2003 Jul-Aug; Vol. 46 (1), pp. 1-9. - Publication Year :
- 2003
-
Abstract
- Smokers differ from nonsmokers in the way they present with acute coronary syndromes and in how they respond to treatment. Although smoking increases the risk of a coronary event and accelerates the progression of established atherosclerosis, paradoxically, smokers have better short-term survival after an acute myocardial infarction, mainly because they are younger and have more favorable coronary anatomy. Thrombolysis appears to be a better treatment in smokers than in nonsmokers, probably because thrombosis plays a more important role in the pathogenesis of acute coronary events in smokers. Patients who continue to smoke after angioplasty or bypass surgery have a worse outcome than nonsmokers or quitters. The 2.5- to 3-fold increase in risk for myocardial infarction or stroke in smokers compared with nonsmokers decreases exponentially after smoking cessation. By 4 years the risk is only slightly higher than the risk of a subject who never smoked.
Details
- Language :
- English
- ISSN :
- 0033-0620
- Volume :
- 46
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Progress in cardiovascular diseases
- Publication Type :
- Academic Journal
- Accession number :
- 12920697
- Full Text :
- https://doi.org/10.1016/s0033-0620(03)00075-6