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A simplified method for purification of annexin V from human placenta.

Authors :
Poghosyan GG
Melkonyan VZ
Mikaelyan MV
Gasparyan VK
Source :
Preparative biochemistry & biotechnology [Prep Biochem Biotechnol] 2003 Aug; Vol. 33 (3), pp. 209-15.
Publication Year :
2003

Abstract

A simplified procedure for purification of annexin V from human placenta was developed. At first, the protein was separated from other proteins in membrane bound form in the presence of Ca2+, then was extracted with EDTA and purified by affinity chromatography on PAAG-immobilized phosphatidylserine. The purified protein gave a single band with a molecular weight of 35,000 in SDS-PAGE.

Details

Language :
English
ISSN :
1082-6068
Volume :
33
Issue :
3
Database :
MEDLINE
Journal :
Preparative biochemistry & biotechnology
Publication Type :
Academic Journal
Accession number :
12916812
Full Text :
https://doi.org/10.1081/PB-120022989