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[Gene expression of the MAGE-1, -3, and -6 antigens in hepatic carcinoma].
- Source :
-
Tumori [Tumori] 2003 Jul-Aug; Vol. 89 (4 Suppl), pp. 103-4. - Publication Year :
- 2003
-
Abstract
- MAGE is a family of genes specifically associated to human melanoma, but also found in hepatocellular carcinoma (HCC). In this study we evaluated the expression of such genes in 41 HCC patients, their correlation with pathological and clinical aspects of cancer, and the impact on prognosis. MAGE are expressed in most of HCC samples (28/41), no correlation was found with type and stage but they may be used as potential target for IT.
- Subjects :
- Aged
Aged, 80 and over
Antigens, Neoplasm biosynthesis
Cancer Vaccines
Carcinoma, Hepatocellular immunology
Carcinoma, Hepatocellular metabolism
Cross-Sectional Studies
Female
Humans
Liver Neoplasms immunology
Liver Neoplasms metabolism
Male
Melanoma-Specific Antigens
Middle Aged
Neoplasm Proteins biosynthesis
Prospective Studies
Antigens, Neoplasm genetics
Carcinoma, Hepatocellular genetics
Gene Expression Regulation, Neoplastic
Liver Neoplasms genetics
Neoplasm Proteins genetics
Subjects
Details
- Language :
- Italian
- ISSN :
- 0300-8916
- Volume :
- 89
- Issue :
- 4 Suppl
- Database :
- MEDLINE
- Journal :
- Tumori
- Publication Type :
- Academic Journal
- Accession number :
- 12903561