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Establishment and characterization of two new cell lines derived from squamous cell carcinoma of the tongue in Chinese patients.
- Source :
-
Anticancer research [Anticancer Res] 1992 Sep-Oct; Vol. 12 (5), pp. 1627-33. - Publication Year :
- 1992
-
Abstract
- Two new cell lines derived from squamous cell carcinoma of the tongue, T1/CUHK and T2/CUHK, have been established in culture. Analysis of the morphology, ultrastructure, chromosome number, spheroid formation and immunohistochemical properties of the two cell lines demonstrated that they are both well characterized. T1/CUHK cells grew relatively faster than T2/CUHK cells. Both cell lines were tumorigenic after inoculation into made mice and showed positive reactivity with HPV 16 DNA probe. The reactivity of both cell lines with HPV 18 DNA probe was weak.
- Subjects :
- Animals
Biopsy
Carcinoma, Squamous Cell surgery
Cell Line
China ethnology
Chromosomes, Human
Culture Techniques methods
DNA Probes
Hong Kong
Humans
Keratins analysis
Mice
Mice, Nude
Neoplasm Transplantation
Papillomaviridae genetics
Papillomaviridae isolation & purification
Tongue Neoplasms surgery
Transplantation, Heterologous
Tumor Cells, Cultured
Carcinoma, Squamous Cell pathology
Tongue Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0250-7005
- Volume :
- 12
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Anticancer research
- Publication Type :
- Academic Journal
- Accession number :
- 1280031