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Performance indicators of organized cervical screening in Romagna (Italy).
- Source :
-
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) [Eur J Cancer Prev] 2003 Jun; Vol. 12 (3), pp. 223-8. - Publication Year :
- 2003
-
Abstract
- The availability of published data from organized cervical screening programmes in southern Europe is scant. In the Italian area of Romagna, a first round of organized screening (based on a 3-yearly Pap smear for women aged 25-64 years) was initiated between December 1995 and January 1997 and was completed in an average of 42 months (range 36-48 months). The target population included 305 478 women. Of these, 253 949 were eligible and received a personal letter of invitation. Age-specific screening performance indicators were calculated according to standard methods. The response rate within 6 months of invitation was 49.1% (n=124 621). The total participation rate including women who presented later was 61.7% (n=156 735). The recall rate was 35.2 per 1000 of participants (n=5514). Positive cytology results were distributed as follows: atypical squamous cells of un-determined significance/atypical glandular cells of undetermined significance (ASCUS/AGUS) 40.1%, low-grade squamous intraepithelial neoplasia (LGSIL) 48.6%, high-grade squamous intraepithelial neoplasia (HGSIL) 10.7% and carcinoma 0.7%. Compliance to colposcopy follow-up was 93.4% (n=5149). The biopsy rate was 52.4% (n=2696) of patients undergoing colposcopy. The detection rate was 4.5 per 1000 of participants (n=707) for CIN2-3 and 0.5 (n=75) for invasive carcinoma. The proportion of microinvasive carcinomas was 36.0% (n=27). The positive predictive value for CIN2-3/carcinoma was 5.8% for the cytology reports of ASCUS/AGUS, 7.6% for those of LGSIL, 76.5% for those of HGSIL, and 100.0% for those of carcinoma (80.4% for combined HGSIL/carcinoma). The ratio of observed to expected (or prevalent to incident) cases of invasive carcinoma was 2.35 (95% confidence interval (CI) 1.85-2.95). In conclusion, most early results of the programme were compatible with an acceptable performance.
- Subjects :
- Adult
Age Factors
Biopsy
Carcinoma, Squamous Cell pathology
Colposcopy
Female
Follow-Up Studies
Humans
Italy epidemiology
Middle Aged
Neoplasm Invasiveness
Neoplasm Staging
Papanicolaou Test
Patient Compliance
Prevalence
Statistics as Topic
Uterine Cervical Neoplasms pathology
Vaginal Smears
Women's Health
Uterine Cervical Dysplasia pathology
Carcinoma, Squamous Cell diagnosis
Mass Screening
Quality Indicators, Health Care
Uterine Cervical Neoplasms diagnosis
Uterine Cervical Dysplasia diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 0959-8278
- Volume :
- 12
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)
- Publication Type :
- Academic Journal
- Accession number :
- 12771561
- Full Text :
- https://doi.org/10.1097/00008469-200306000-00009