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(Z)-sarcodictyin A, a new highly cytotoxic diterpenoid from the soft coral Bellonella albiflora.
- Source :
-
Journal of natural products [J Nat Prod] 2003 Apr; Vol. 66 (4), pp. 524-7. - Publication Year :
- 2003
-
Abstract
- A new cytotoxic diterpene, (Z)-sarcodictyin A, was isolated from the Japanese soft coral Bellonella albiflora.(1) Its structure was elucidated on the basis of 1D and 2D NMR analysis and chemical degradation. (Z)-Sarcodictyin A showed strong cytotoxicity against HeLa human cervix cells.
- Subjects :
- Alkaloids chemistry
Alkaloids pharmacology
Animals
Antineoplastic Agents chemistry
Antineoplastic Agents pharmacology
Diterpenes chemistry
Diterpenes pharmacology
Drug Screening Assays, Antitumor
Female
HeLa Cells drug effects
Humans
Japan
Molecular Conformation
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Stereoisomerism
Tumor Cells, Cultured drug effects
Uterine Cervical Neoplasms
Alkaloids isolation & purification
Antineoplastic Agents isolation & purification
Cnidaria chemistry
Diterpenes isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0163-3864
- Volume :
- 66
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of natural products
- Publication Type :
- Academic Journal
- Accession number :
- 12713406
- Full Text :
- https://doi.org/10.1021/np0205452