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Synthesis of a tricyclic mescaline analogue by catalytic C-H bond activation.

Authors :
Ahrendt KA
Bergman RG
Ellman JA
Source :
Organic letters [Org Lett] 2003 Apr 17; Vol. 5 (8), pp. 1301-3.
Publication Year :
2003

Abstract

[reaction: see text] A tetrahydrobis(benzofuran) mescaline analogue has been prepared in six steps and 38% overall yield from (4'-O-methyl)methyl gallate. The key step in this synthesis is a tandem cyclization reaction via directed C[bond]H activation followed by olefin insertion.

Details

Language :
English
ISSN :
1523-7060
Volume :
5
Issue :
8
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
12688744
Full Text :
https://doi.org/10.1021/ol034228d