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[Molecular genetic diagnosis of autosomal dominant polycystic kidney disease].

Authors :
Reiterová J
Merta M
Stekrová J
Tesar V
Source :
Sbornik lekarsky [Sb Lek] 2002; Vol. 103 (4), pp. 435-42.
Publication Year :
2002

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary disease of kidney. The renal function is impaired by the development of the cysts. Patients with ADPKD have often affected other organs. Nowadays there is established linkage analysis of ADPKD using microsatellites in Czech Republic. Molecular analysis allows presymptomatic diagnosis in risk-individuals and prenatal diagnosis in affected families. The detection of mutations is performed supporting by the grant in Czech Republic. The detection of mutation will contribute to more precise diagnosis in controversial cases.

Details

Language :
Czech
ISSN :
0036-5327
Volume :
103
Issue :
4
Database :
MEDLINE
Journal :
Sbornik lekarsky
Publication Type :
Academic Journal
Accession number :
12688156