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[Prognostic factors of 60 nasal cavity carcinoma patients].
- Source :
-
Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2002 Nov; Vol. 24 (6), pp. 592-4. - Publication Year :
- 2002
-
Abstract
- Objective: To evaluate the treatment modalities and the prognostic factors of nasal cavity carcinoma.<br />Methods: A retrospective study was done on 60 nasal cavity carcinoma patients treated from 1985 to 1992. Thirty-four patients received radiotherapy alone and 26 patients received surgery plus radiotherapy. Kaplan-Meier method was used to evaluate the survival, Log-rank test to assess the difference between these two groups and Cox proportional hazard model by multivariate analysis.<br />Results: The overall 5- and 10-year survival rates were 55.9% and 36.9% respectively. The 5- and 10-year survival rates were 79.0% and 57.9% in patients with early lesions (stage I, II) and 44.1% and 26.0% in patients with advanced lesions (stage III, IV) (P = 0.005). There was no significant difference in the survival rate between radiotherapy alone and radiotherapy plus surgery (P = 0.33). Patients with squamous cell carcinoma had obviously poorer survival rate than patients with adenocarcinoma (P = 0.04). Patients with positive nodes had a lower survival rate compared with negative node patients (P = 0.09).<br />Conclusion: Histological type and clinical stage, but not method of treatment or neck node metastasis, are the important prognostic factors.
- Subjects :
- Adolescent
Adult
Aged
Combined Modality Therapy
Female
Humans
Lymphatic Metastasis
Male
Middle Aged
Multivariate Analysis
Neck
Neoplasm Staging
Nose Neoplasms mortality
Nose Neoplasms radiotherapy
Prognosis
Retrospective Studies
Survival Rate
Nasal Cavity
Nose Neoplasms diagnosis
Nose Neoplasms surgery
Subjects
Details
- Language :
- Chinese
- ISSN :
- 0253-3766
- Volume :
- 24
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Zhonghua zhong liu za zhi [Chinese journal of oncology]
- Publication Type :
- Academic Journal
- Accession number :
- 12667333