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In vitro evaluation of combination of terbinafine with itraconazole or amphotericin B against Zygomycota.
- Source :
-
Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2003 Mar; Vol. 45 (3), pp. 199-202. - Publication Year :
- 2003
-
Abstract
- The combined activity in vitro of amphotericin B/terbinafine and itraconazole/terbinafine was assessed against 17 clinical isolates of Zygomycota using a checkerboard technique. Itraconazole/terbinafine combination exhibited a potent synergistic effect against the most of strains. Amphotericin B/terbinafine combination showed an indifferent interaction for Rhizopus oryzae, and an additive effect for the other species.
- Subjects :
- Colony Count, Microbial
Drug Interactions
Female
Fungi isolation & purification
Humans
Male
Microbial Sensitivity Tests
Mycoses diagnosis
Mycoses drug therapy
Sensitivity and Specificity
Terbinafine
Amphotericin B pharmacology
Antifungal Agents pharmacology
Fungi drug effects
Itraconazole pharmacology
Naphthalenes pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0732-8893
- Volume :
- 45
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Diagnostic microbiology and infectious disease
- Publication Type :
- Academic Journal
- Accession number :
- 12663161
- Full Text :
- https://doi.org/10.1016/s0732-8893(02)00509-6