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[Disturbance of immune characteristics of the mucous membranes of the respiratory tract in bronchopulmonary diseases in children].
- Source :
-
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 2003 Jan-Feb (1), pp. 72-4. - Publication Year :
- 2003
-
Abstract
- A total of 100 children with bronchopulmonary diseases were examined. Of these, in 80 bronchial asthma and in 20 children acute pneumonia were diagnosed. The deficiency of local cell mediated and humoral factors on the mucous membranes of the upper respiratory tracts was established. In the squamous and columnar epithelium cells an increased destruction and cytolysis was noted leading to disturbances in the integrity of the protective barrier of the epithelial cover. In addition, this study revealed the deficiency of neutrophilic leukocytes, pronounced local eosinophilia and the low level of humoral protective factors. In acute pneumonia an increase in the amount of neutrophilic leukocytes in the secretion of the nasal cavity together with the appearance of destructive processes in epithelial cells took place. Pronounced deficiency in serum IgA and IgG was accompanied by compensatory increase in secretory IgA.
- Subjects :
- Acute Disease
Adolescent
Asthma blood
Cell Count
Child
Eosinophils cytology
Epithelial Cells pathology
Female
Humans
Immunoglobulin A blood
Immunoglobulin A, Secretory analysis
Immunoglobulin G blood
Male
Neutrophils cytology
Pneumonia blood
Respiratory Mucosa metabolism
Respiratory Mucosa pathology
Saliva immunology
Asthma immunology
Pneumonia immunology
Respiratory Mucosa immunology
Subjects
Details
- Language :
- Russian
- ISSN :
- 0372-9311
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Zhurnal mikrobiologii, epidemiologii i immunobiologii
- Publication Type :
- Academic Journal
- Accession number :
- 12630360