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Decreased carotenoid concentrations due to dietary sucrose polyesters do not affect possible markers of disease risk in humans.
- Source :
-
The Journal of nutrition [J Nutr] 2003 Mar; Vol. 133 (3), pp. 720-6. - Publication Year :
- 2003
-
Abstract
- Excessive consumption of energy and fat increases the risk for obesity. Snacks containing sucrose polyesters (SPE) as a dietary fat replacer are on the market in the United States. SPE products have been shown to lower concentrations of serum carotenoids in short-term studies. Experimental studies on the longer-term effects on health of decreased carotenoid concentrations are lacking. A 1-y randomized, double-blind, placebo-controlled parallel trial was performed. Subjects (n = 380) with a habitual low or high fruit and vegetable intake were assigned to the treatments (0, 7, 10 or 17 g/d SPE). SPE was given in the form of spreads, chips or both. The groups were compared for serum carotenoids, vitamins and markers of oxidative damage, eye health, cardiovascular health and immune status. After 1 y, serum lipid-adjusted carotenoids showed the largest decrease in the SPE chips and spread group (17 g/d) compared with the control group [alpha-carotene 33%; beta-carotene 31%, lycopene 24%, beta-cryptoxanthin 18%, lutein 18% (all P < 0.001) and zeaxanthin 13% (P < 0.05)]. Consumption of SPE spread (10 g/d SPE) decreased carotenoid concentrations by 11-29% (all P < 0.05). SPE chips (7 g/d SPE) decreased zeaxanthin (11%), beta-carotene (12%) and alpha-carotene (21%; all P < 0.05). Serum lipid adjusted alpha-tocopherol decreased significantly by 6-8% (all P < 0.001) in all SPE groups. No negative effects were observed on markers of oxidation, eye health, cardiovascular health or immune status. This study shows that decreases in serum carotenoid concentrations do not affect possible markers of disease risk.
- Subjects :
- Adolescent
Adult
Aged
Body Weight
Cardiovascular Diseases diagnosis
Dietary Fats, Unsaturated administration & dosage
Double-Blind Method
Endothelium, Vascular physiology
Eye Diseases diagnosis
Fatty Acids administration & dosage
Female
Humans
Immunity
Lipid Peroxidation
Lipids blood
Macula Lutea anatomy & histology
Male
Middle Aged
Patient Compliance
Placebos
Risk Factors
Sucrose administration & dosage
Xanthophylls
Zeaxanthins
alpha-Tocopherol blood
beta Carotene blood
Carotenoids blood
Dietary Fats, Unsaturated adverse effects
Fatty Acids adverse effects
Health Status
Sucrose adverse effects
Sucrose analogs & derivatives
beta Carotene analogs & derivatives
Subjects
Details
- Language :
- English
- ISSN :
- 0022-3166
- Volume :
- 133
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Journal of nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 12612143
- Full Text :
- https://doi.org/10.1093/jn/133.3.720