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Demyelination and cortical reorganization: functional MRI data from a case of subacute combined degeneration.
- Source :
-
NeuroImage [Neuroimage] 2003 Feb; Vol. 18 (2), pp. 558-63. - Publication Year :
- 2003
-
Abstract
- Although it is accepted that functional changes of the cortex can occur in patients with white matter diseases of the brain and might have an adaptive role in limiting the clinical consequences of subcortical injury, the pathological substrates able to elicit such cortical changes are still unknown. This multiparametric magnetic resonance study of a patient with an early diagnosis of subacute combined degeneration suggests that demyelination alone does not necessarily induce adaptive functional changes of the cerebral cortex.
- Subjects :
- Demyelinating Diseases pathology
Humans
Male
Middle Aged
Motor Cortex pathology
Pyramidal Tracts pathology
Reference Values
Somatosensory Cortex pathology
Spinal Cord pathology
Cerebral Cortex pathology
Demyelinating Diseases diagnosis
Diffusion Magnetic Resonance Imaging
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Neuronal Plasticity physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1053-8119
- Volume :
- 18
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- NeuroImage
- Publication Type :
- Academic Journal
- Accession number :
- 12595207
- Full Text :
- https://doi.org/10.1016/s1053-8119(02)00011-3