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The ldb1 mutant of Saccharomyces cerevisiae is defective in Pmr1p, the yeast secretory pathway/Golgi Ca(2+)/Mn(2+)-ATPase.
- Source :
-
FEMS microbiology letters [FEMS Microbiol Lett] 2003 Feb 14; Vol. 219 (1), pp. 137-42. - Publication Year :
- 2003
-
Abstract
- The LDB1 gene of Saccharomyces cerevisiae was identified by complementation of the ldb1 mutant phenotype with a genomic library. We found that the ldb1 defect is complemented by PMR1 which codes for the yeast secretory pathway/Golgi Ca(2+)/Mn(2+)-ATPase. Besides that, the analysis of a null mutation of the PMR1 gene revealed a phenotype identical to that of ldb1 mutant. Thus, LDB1 must be considered a synonym of PMR1.
- Subjects :
- Calcium metabolism
Calcium-Transporting ATPases genetics
Calcium-Transporting ATPases metabolism
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Fungal
Genetic Complementation Test
Manganese metabolism
Saccharomyces cerevisiae genetics
Saccharomyces cerevisiae growth & development
Saccharomyces cerevisiae Proteins metabolism
Transformation, Genetic
Calcium-Transporting ATPases deficiency
Golgi Apparatus enzymology
Mutation
Saccharomyces cerevisiae enzymology
Saccharomyces cerevisiae Proteins genetics
Subjects
Details
- Language :
- English
- ISSN :
- 0378-1097
- Volume :
- 219
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- FEMS microbiology letters
- Publication Type :
- Academic Journal
- Accession number :
- 12594035
- Full Text :
- https://doi.org/10.1016/S0378-1097(03)00002-8