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Regional cerebral blood flow changes during visually induced subjective sadness in healthy elderly persons.
- Source :
-
The Journal of neuropsychiatry and clinical neurosciences [J Neuropsychiatry Clin Neurosci] 2003 Winter; Vol. 15 (1), pp. 35-44. - Publication Year :
- 2003
-
Abstract
- This study examined regional cerebral blood flow (rCBF) changes associated with visually induced sad affect in healthy elderly persons. Subjects viewed sadness-laden, happiness-laden, and emotionally neutral image sets while rCBF was recorded using [(15)O] water PET. The sad image set included human faces and scenery/objects ("scenes"). To control for secondary sensory processing, the neutral and happy comparison sets included exclusively either human faces or scenes. During the sad condition, the ventral prefrontal and temporal cortices were more active compared with happy and neutral scenes conditions and the thalamus was more active compared with happy and neutral faces conditions. Ventral prefrontal cortex and thalamus were associated with processing of sad visual stimuli, whether compared with neutral or happy stimuli. The specific findings associated with sad affect were contingent on the comparison stimuli content (scenes or human faces), not affect (i.e., comparison with neutral or happy conditions).
- Subjects :
- Aged
Brain Mapping
Cerebral Cortex diagnostic imaging
Female
Happiness
Humans
Imagination physiology
Magnetic Resonance Imaging
Male
Middle Aged
Nerve Net blood supply
Nerve Net diagnostic imaging
Pattern Recognition, Visual physiology
Prefrontal Cortex blood supply
Prefrontal Cortex diagnostic imaging
Reference Values
Temporal Lobe blood supply
Temporal Lobe diagnostic imaging
Thalamus blood supply
Thalamus diagnostic imaging
Affect physiology
Cerebral Cortex blood supply
Tomography, Emission-Computed
Subjects
Details
- Language :
- English
- ISSN :
- 0895-0172
- Volume :
- 15
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The Journal of neuropsychiatry and clinical neurosciences
- Publication Type :
- Academic Journal
- Accession number :
- 12556569
- Full Text :
- https://doi.org/10.1176/jnp.15.1.35