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A possible outbreak of Streptococcus pneumoniae invasive infection in children in Ibadan, Nigeria.
- Source :
-
African journal of medicine and medical sciences [Afr J Med Med Sci] 2002 Jun; Vol. 31 (2), pp. 141-3. - Publication Year :
- 2002
-
Abstract
- Streptococcus pneumoniae is an important aetiological agent of infections in children worldwide. The isolation rate of the bacteria has been strikingly low in the recent past in Nigeria. In a study of 1000 blood samples from patients, out of which 642 were from children in Ibadan between May 1999 and December 2000, 14 isolates of Streptococcus pneumoniae were obtained (a prevalence rate of 1.4%). All the isolates were from children and clustered between 13th September and 22nd October 1999, period of 40 days and thereafter no more organisms were isolated. Antibiotic sensitivity testing of all isolates by disc diffusion method showed resistance to cotrimoxazole, tetracycline and penicillin to be 14%, 21% and 36% respectively. All the isolates were sensitive to chloramphenicol and erythromycin. No fatalities were recorded among the children. This may have indicated an outbreak and underscores the urgency for an epidemiological database in Nigeria to ascertain the exact clinical burden of S. pnemoniae infections so as to determine the appropriate vaccine strategies required for Nigerian children.
- Subjects :
- Age Distribution
Child
Child, Preschool
Cluster Analysis
Drug Resistance, Multiple, Bacterial
Female
Humans
Incidence
Infant
Infant, Newborn
Male
Microbial Sensitivity Tests
Needs Assessment
Nigeria epidemiology
Pneumococcal Infections prevention & control
Population Surveillance
Risk Factors
Seasons
Sex Distribution
Vaccination
Child Welfare statistics & numerical data
Disease Outbreaks statistics & numerical data
Pneumococcal Infections epidemiology
Pneumococcal Infections microbiology
Streptococcus pneumoniae isolation & purification
Urban Health statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 0309-3913
- Volume :
- 31
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- African journal of medicine and medical sciences
- Publication Type :
- Academic Journal
- Accession number :
- 12518910