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Steroidal glycosides from the leaves of Cestrum nocturnum.
- Source :
-
Journal of natural products [J Nat Prod] 2002 Dec; Vol. 65 (12), pp. 1863-8. - Publication Year :
- 2002
-
Abstract
- Further phytochemical analysis aimed at the steroidal glycoside constituents of the leaves of Cestrum nocturnum has resulted in the isolation of eight new steroidal glycosides (1-8), which were classified into a spirostanol saponin (1), a furostanol saponin (2), a pseudo-furostanol saponin (3), two pregnane glycosides (4, 5), two cholestane glycosides (6, 7), and pregnane-carboxylic acid gamma-lactone glycoside (8), and of two known spirostanol glycosides (9, 10). The structures of the new compounds were elucidated on the basis of chemical and spectroscopic evidence.
- Subjects :
- Acetylation
Antineoplastic Agents, Phytogenic chemistry
Antineoplastic Agents, Phytogenic pharmacology
Carcinoma, Squamous Cell
Catalysis
Doxorubicin pharmacology
Drug Screening Assays, Antitumor
Glycosides chemistry
Glycosides pharmacology
Humans
Hydrolysis
Japan
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Leaves chemistry
Stereoisomerism
Steroids chemistry
Steroids pharmacology
Tumor Cells, Cultured drug effects
Antineoplastic Agents, Phytogenic isolation & purification
Cestrum chemistry
Glycosides isolation & purification
Plants, Medicinal chemistry
Steroids isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0163-3864
- Volume :
- 65
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Journal of natural products
- Publication Type :
- Academic Journal
- Accession number :
- 12502329
- Full Text :
- https://doi.org/10.1021/np020276f