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[Nutrition and health--fish fatty acids against fatal coronary heart disease].
- Source :
-
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2002 Nov 23; Vol. 146 (47), pp. 2229-33. - Publication Year :
- 2002
-
Abstract
- There are strong indications that eating (fatty) fish or n-3 fatty acids from fish reduces the risk of fata coronary heart disease (CHD). Observational studies in the general population show that consumption of moderate amounts of fish or n-3 fatty acids from fish are associated with a lower risk of fatal coronary heart disease and in particular sudden cardiac death. The most plausible hypothesis is that n-3 fatty acids reduce the risk of CHD mortality via anti-arrhythmic effects. Two clinical intervention trials show that prescription of fish or n-3 fatty acids to patients with prior myocardial infarction is effective in preventing mortality due to CHD. Ongoing trials will have to prove the effectiveness of a low dose of n-3 fatty acids and show that the underlying mechanism involves a protective effect against life-threatening arrhythmias. In addition to other recommendations for a healthier diet and lifestyle, consumption of one or two fatty fish meals a week is a highly effective and safe measure to reduce CHD mortality in both the general population and patients.
- Subjects :
- Animals
Coronary Disease mortality
Death, Sudden, Cardiac prevention & control
Fatty Acids, Omega-3 administration & dosage
Fatty Acids, Omega-3 therapeutic use
Fatty Acids, Unsaturated therapeutic use
Fish Oils therapeutic use
Fishes
Humans
Myocardial Infarction mortality
Myocardial Infarction prevention & control
Netherlands
Risk Factors
Coronary Disease prevention & control
Fatty Acids, Unsaturated administration & dosage
Fish Oils administration & dosage
Nutritional Physiological Phenomena
Subjects
Details
- Language :
- Dutch; Flemish
- ISSN :
- 0028-2162
- Volume :
- 146
- Issue :
- 47
- Database :
- MEDLINE
- Journal :
- Nederlands tijdschrift voor geneeskunde
- Publication Type :
- Academic Journal
- Accession number :
- 12481519