Back to Search Start Over

[Nutrition and health--fish fatty acids against fatal coronary heart disease].

Authors :
Zock PL
Kromhout D
Source :
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2002 Nov 23; Vol. 146 (47), pp. 2229-33.
Publication Year :
2002

Abstract

There are strong indications that eating (fatty) fish or n-3 fatty acids from fish reduces the risk of fata coronary heart disease (CHD). Observational studies in the general population show that consumption of moderate amounts of fish or n-3 fatty acids from fish are associated with a lower risk of fatal coronary heart disease and in particular sudden cardiac death. The most plausible hypothesis is that n-3 fatty acids reduce the risk of CHD mortality via anti-arrhythmic effects. Two clinical intervention trials show that prescription of fish or n-3 fatty acids to patients with prior myocardial infarction is effective in preventing mortality due to CHD. Ongoing trials will have to prove the effectiveness of a low dose of n-3 fatty acids and show that the underlying mechanism involves a protective effect against life-threatening arrhythmias. In addition to other recommendations for a healthier diet and lifestyle, consumption of one or two fatty fish meals a week is a highly effective and safe measure to reduce CHD mortality in both the general population and patients.

Details

Language :
Dutch; Flemish
ISSN :
0028-2162
Volume :
146
Issue :
47
Database :
MEDLINE
Journal :
Nederlands tijdschrift voor geneeskunde
Publication Type :
Academic Journal
Accession number :
12481519