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A MyoD-dependent differentiation checkpoint: ensuring genome integrity.

Authors :
Polesskaya A
Rudnicki MA
Source :
Developmental cell [Dev Cell] 2002 Dec; Vol. 3 (6), pp. 757-8.
Publication Year :
2002

Abstract

In a recent paper, the concept of a genotoxic stress-induced differentiation checkpoint has been proposed. The suggested function of this checkpoint is to preserve the integrity of the genome in terminally differentiated cells.

Subjects

Subjects :
Animals
DNA Damage genetics
Genome
Humans
Muscle, Skeletal growth & development
Muscle, Skeletal metabolism
MyoD Protein metabolism
Myoblasts, Skeletal cytology
Cell Cycle genetics
Cell Differentiation genetics
Genes, cdc physiology
Muscle, Skeletal embryology
MyoD Protein genetics
Myoblasts, Skeletal metabolism

Details

Language :
English
ISSN :
1534-5807
Volume :
3
Issue :
6
Database :
MEDLINE
Journal :
Developmental cell
Publication Type :
Academic Journal
Accession number :
12479798
Full Text :
https://doi.org/10.1016/s1534-5807(02)00372-6
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