Back to Search
Start Over
MnDPDP enhanced magnetic resonance imaging of focal liver lesions.
- Source :
-
Clinical radiology [Clin Radiol] 2002 Dec; Vol. 57 (12), pp. 1047-57. - Publication Year :
- 2002
-
Abstract
- Mangafodipir trisodium (MnDPDP) is a contrast agent for use in magnetic resonance imaging (MRI) of the liver. The agent is taken up by normal hepatocytes resulting in increased signal on T1-weighted imaging, and is excreted in the biliary system. Hepatocyte-containing liver neoplasms such as hepatomas or focal nodular hyperplasia (FNH), take up MnDPDP and demonstrate varying degrees of enhancement. Metastatic liver deposits and primary liver tumours of non-hepatocyte origin do not typically enhance with MnDPDP thus increasing their conspicuity compared with pre-contrast T1-weighted images. Metastases may demonstrate rim enhancement particularly on delayed imaging at 24 h, which can increase their conspicuity, thus allowing better visualization of small lesions. Functional biliary obstruction due to liver metastases can also result in wedge shaped areas of parenchymal enhancement. The MRI features of various focal liver after continuance with lesions following MnDPDP are discussed and illustrated including primary lesions such as hepatoma and secondary metastases.
- Subjects :
- Adenoma, Liver Cell diagnosis
Adult
Aged
Cholangiocarcinoma diagnosis
Female
Focal Nodular Hyperplasia diagnosis
Hemangioma diagnosis
Humans
Liver Neoplasms diagnosis
Liver Neoplasms secondary
Magnetic Resonance Imaging methods
Magnetic Resonance Imaging standards
Male
Middle Aged
Contrast Media
Edetic Acid analogs & derivatives
Liver Diseases diagnosis
Pyridoxal Phosphate analogs & derivatives
Subjects
Details
- Language :
- English
- ISSN :
- 0009-9260
- Volume :
- 57
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Clinical radiology
- Publication Type :
- Academic Journal
- Accession number :
- 12475527
- Full Text :
- https://doi.org/10.1053/crad.2002.1117