Back to Search
Start Over
The EZH2 polycomb transcriptional repressor--a marker or mover of metastatic prostate cancer?
- Source :
-
Cancer cell [Cancer Cell] 2002 Nov; Vol. 2 (5), pp. 349-50. - Publication Year :
- 2002
-
Abstract
- The recent finding of overexpression of the polycomb group transcriptional repressor EZH2 in prostate cancer raises the possibility that transcriptional regulation at the chromatin level may play a role in the development of the metastatic phenotype and suggests new avenues of exploration with respect to patient stratification and therapeutics.
- Subjects :
- DNA-Binding Proteins
Enhancer of Zeste Homolog 2 Protein
Gene Expression Profiling
Gene Expression Regulation
Humans
Male
Oligonucleotide Array Sequence Analysis
Polycomb Repressive Complex 2
Prostatic Neoplasms surgery
Proteins analysis
RNA, Messenger genetics
RNA, Messenger metabolism
Transcription Factors
Transcription, Genetic
Treatment Outcome
Biomarkers, Tumor
Prostatic Neoplasms genetics
Prostatic Neoplasms secondary
Proteins metabolism
Repressor Proteins genetics
Repressor Proteins physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1535-6108
- Volume :
- 2
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Cancer cell
- Publication Type :
- Academic Journal
- Accession number :
- 12450788
- Full Text :
- https://doi.org/10.1016/s1535-6108(02)00187-3