Effect of pine resin and Biopin ointment on T and B cell immunity.

We studied the effects of pine resin and Biopin ointment used for the therapy of burns, wounds, purulent and inflammatory diseases on differentiation of T lymphocyte precursors, lymphocyte proliferation in the thymus and spleen, and production of tumor necrosis factor and interleukins 1, 2, and 6 by splenocytes and peripheral blood leukocytes. The wound-healing effect of these preparations is determined by their pronounced immunomodulatory properties.