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The importance of distributed sampling in blocked functional magnetic resonance imaging designs.
- Source :
-
NeuroImage [Neuroimage] 2002 Nov; Vol. 17 (3), pp. 1203-6. - Publication Year :
- 2002
-
Abstract
- In this study we demonstrate the importance of distributed sampling of peristimulus time in blocked design fMRI studies. Distributed sampling ensures all the components of an event-related hemodynamic response are sampled and avoids the bias incurred when stimulus presentation is time-locked to data acquisition. We found that differences in the temporal offset between stimulus presentation and data acquisition had a significant effect on some language-related activations. These effects, induced by simply shifting stimulus presentation by a fraction of the interscan interval, suggest that fixed sampling does indeed bias estimated responses, even in blocked designs.
- Subjects :
- Adult
Dominance, Cerebral physiology
Female
Hemodynamics physiology
Humans
Male
Oxygen blood
Reference Values
Attention physiology
Brain Mapping methods
Cerebral Cortex physiology
Image Processing, Computer-Assisted methods
Imaging, Three-Dimensional methods
Magnetic Resonance Imaging methods
Reading
Subjects
Details
- Language :
- English
- ISSN :
- 1053-8119
- Volume :
- 17
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- NeuroImage
- Publication Type :
- Academic Journal
- Accession number :
- 12414260
- Full Text :
- https://doi.org/10.1006/nimg.2002.1242