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Multiphasic disseminated encephalomyelitis associated with streptococcal infection.
- Source :
-
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society [Eur J Paediatr Neurol] 2002; Vol. 6 (6), pp. 327-9. - Publication Year :
- 2002
-
Abstract
- Multiphasic disseminated encephalomyelitis (MDEM) is a rare peculiar diagnosis which is defined as acute demyelinating central nervous system disease with relapses occurring only within 4 weeks of initial manifestation. This report describes the case of a 6-year-old boy with MDEM diagnosed by clinical findings and magnetic resonance imaging. The disease had a biphasic evolution, and with a second course of high-dose corticosteroids a complete recovery without further relapse was obtained during the following 18 months. Serological evidence of streptococcal infection as specific trigger for MDEM was given. Thus this report raises the question whether an additional penicillin prophylaxis could be valuable for prevention of streptococcus-associated MDEM relapses.
- Subjects :
- Anti-Inflammatory Agents therapeutic use
Brain pathology
Child
Drug Administration Schedule
Electroencephalography
Encephalomyelitis, Acute Disseminated diagnosis
Encephalomyelitis, Acute Disseminated drug therapy
Humans
Magnetic Resonance Imaging
Male
Steroids
Streptococcal Infections drug therapy
Brain microbiology
Encephalomyelitis, Acute Disseminated microbiology
Streptococcal Infections complications
Subjects
Details
- Language :
- English
- ISSN :
- 1090-3798
- Volume :
- 6
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
- Publication Type :
- Academic Journal
- Accession number :
- 12401458
- Full Text :
- https://doi.org/10.1016/s1090-3798(02)90621-5