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A new method for synthesis of 7-deoxytaxane analogues by hydrogenation of delta(6,7)-taxane derivatives.

Authors :
Takeda Y
Yoshino T
Uoto K
Terasawa H
Soga T
Source :
Chemical & pharmaceutical bulletin [Chem Pharm Bull (Tokyo)] 2002 Oct; Vol. 50 (10), pp. 1398-400.
Publication Year :
2002

Abstract

A new method for the synthesis of 7-deoxytaxane analogues has been established through hydrogenation of Delta(6,7)-taxane derivatives. Among several catalysts examined, Pd-C was found to be a most effective catalyst for the preparation of target compound.

Details

Language :
English
ISSN :
0009-2363
Volume :
50
Issue :
10
Database :
MEDLINE
Journal :
Chemical & pharmaceutical bulletin
Publication Type :
Academic Journal
Accession number :
12372874
Full Text :
https://doi.org/10.1248/cpb.50.1398