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Motoring around the Golgi.

Authors :
Allan VJ
Thompson HM
McNiven MA
Source :
Nature cell biology [Nat Cell Biol] 2002 Oct; Vol. 4 (10), pp. E236-42.
Publication Year :
2002

Abstract

The Golgi apparatus is a dynamic organelle through which nascent secretory and transmembrane proteins are transported, post-translationally modified and finally packaged into carrier vesicles for transport along the cytoskeleton to a variety of destinations. In the past decade, studies have shown that a number of 'molecular motors' are involved in maintaining the proper structure and function of the Golgi apparatus. Here, we review just some of the many functions performed by these mechanochemical enzymes - dyneins, kinesins, myosins and dynamin - in relation to the Golgi apparatus.

Details

Language :
English
ISSN :
1465-7392
Volume :
4
Issue :
10
Database :
MEDLINE
Journal :
Nature cell biology
Publication Type :
Academic Journal
Accession number :
12360306
Full Text :
https://doi.org/10.1038/ncb1002-e236