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Complete characterization of the DQB1 first exon polymorphism.

Authors :
Pascual M
López-Nevot MA
Caballero A
Alonso A
Zanelli E
Martín J
Source :
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics [Eur J Immunogenet] 2002 Oct; Vol. 29 (5), pp. 447-8.
Publication Year :
2002

Abstract

Here we report an additional source of variation resulting from genetic polymorphism in HLA-DQbeta1 genes, namely, allelic diversity in the first exon of the HLA-DQB1 locus, which encodes the leader peptide sequence. Six different variants, including a novel polymorphic site, were detected among the DBQ1 haplotypes.

Details

Language :
English
ISSN :
0960-7420
Volume :
29
Issue :
5
Database :
MEDLINE
Journal :
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics
Publication Type :
Academic Journal
Accession number :
12358858
Full Text :
https://doi.org/10.1046/j.1365-2370.2002.00344.x