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Optimisation of a culture medium containing fish silage for L-lysine production by Corynebacterium glutamicum.
- Source :
-
Bioresource technology [Bioresour Technol] 2002 Nov; Vol. 85 (2), pp. 207-11. - Publication Year :
- 2002
-
Abstract
- In a first step the effects of 10 components of a culture medium designed for L-lysine production were evaluated with a 2(10-6) factorial design. Among them, glucose, fish silage, and ammonium sulphate showed a significant effect. In a second step, an orthogonal-central composite experimental design and response surface methodology was performed with five from the 10 initial compounds. The determination coefficient (R2) of the fitted second-order model was 0.990. L-lysine production with the optimised medium increased 2.6 times as compared with the original medium.
Details
- Language :
- English
- ISSN :
- 0960-8524
- Volume :
- 85
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Bioresource technology
- Publication Type :
- Academic Journal
- Accession number :
- 12227548
- Full Text :
- https://doi.org/10.1016/s0960-8524(02)00084-6