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[Cured from Hodgkin's disease].
- Source :
-
Bulletin du cancer [Bull Cancer] 2002 Jul-Aug; Vol. 89 (7-8), pp. 666-70. - Publication Year :
- 2002
-
Abstract
- Hodgkin's disease can be cured from 80 to 90% of cases with a regular improvement of therapeutic results since 1960. We detailed the remission criteria with a focus on post therapeutic residual masses which did not influence the relapse rate. The follow-up of patients in remission is made as an outbasis care every 4 months during the first year than every 6 months with a routine bilan for 10 years. Some adverse events can occur with first, the acute leukemia arising before 10 years, this risk is decreasing with the disminished use of MOPP chemotherapy. The other solid tumors occur later and are related to the patient age, the type of treatment given and individual factors. Thyroid diseases are frequent but mostly benign needing only consumption of thyroid extracts. Fertility is directly related to chemotherapy (including alkylating agents) and to pelvic radiation therapy. With the current use of ABVD-type chemotherapy the preservation of fertility is good but there is a risk for long term cardiopulmonary toxicity almost for the older patients receiving together mediastinal radiation therapy. At the end most long-term survivors of Hodgkin's disease recover a normal socioprofessional life, while reporting a longer duration of fatigue and many children were born after treatments.
- Subjects :
- Antineoplastic Combined Chemotherapy Protocols administration & dosage
Antineoplastic Combined Chemotherapy Protocols adverse effects
Bleomycin administration & dosage
Bleomycin adverse effects
Cause of Death
Dacarbazine administration & dosage
Dacarbazine adverse effects
Doxorubicin administration & dosage
Doxorubicin adverse effects
Fertility drug effects
Hodgkin Disease mortality
Hodgkin Disease psychology
Humans
Incidence
Mechlorethamine administration & dosage
Mechlorethamine adverse effects
Neoplasm Recurrence, Local epidemiology
Neoplasms, Second Primary epidemiology
Prednisone administration & dosage
Prednisone adverse effects
Procarbazine administration & dosage
Procarbazine adverse effects
Remission Induction
Risk Factors
Time Factors
Vinblastine administration & dosage
Vinblastine adverse effects
Vincristine administration & dosage
Vincristine adverse effects
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Hodgkin Disease drug therapy
Subjects
Details
- Language :
- French
- ISSN :
- 0007-4551
- Volume :
- 89
- Issue :
- 7-8
- Database :
- MEDLINE
- Journal :
- Bulletin du cancer
- Publication Type :
- Academic Journal
- Accession number :
- 12206979