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[Prognostic value of gene expression profiling using cDNA arrays in lymphomas].

Authors :
Bertucci F
Salas S
Nasser V
Houlgatte R
Birnbaum D
Xerri L
Source :
Bulletin du cancer [Bull Cancer] 2002 Jul-Aug; Vol. 89 (7-8), pp. 661-5.
Publication Year :
2002

Abstract

Lymphomas are the most frequent haematological malignancies in France. Their histoclinical heterogeneity reflects their complex and combinatorial nature which remains poorly elucidated at the molecular level. Today, DNA arrays allow to tackle this diversity by measuring the mRNA expression level of thousands of genes simultaneously in one sample. Recent publications show the potential of DNA arrays to improve the prognostic classification of diffuse large B cell lymphomas and of Hodgkin's lymphoma, by identifying new tumour classes unrecognised by classical factors.

Details

Language :
French
ISSN :
0007-4551
Volume :
89
Issue :
7-8
Database :
MEDLINE
Journal :
Bulletin du cancer
Publication Type :
Academic Journal
Accession number :
12206978