Back to Search Start Over

[The expression and significance of VEGF mRNA and bFGF mRNA in the malignant neoplasms of ovary].

Authors :
Li L
Liu YZ
Wu YL
Source :
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University [Hunan Yi Ke Da Xue Xue Bao] 2000 Aug 28; Vol. 25 (4), pp. 406-8.
Publication Year :
2000

Abstract

The expression and significance of VEGF mRNA and bFGF mRNA in the malignant neoplasms of ovary were studied by in situ hybridization technique. The results were that the positive rates of VEGF mRNA and bFGF mRNA were higher in the serous adenocarcinoma and embryonal carcinoma than that in the mucous adenocarcinoma and granulosa cell tumor. The positive rates of VEGF mRNA and bFGF mRNA were lower in the cases of clinical Stage I and without metastasis than that of clinical Stage III-IV and with metastasis. The results suggest that the expressions of VEGF mRNA and bFGF mRNA might be related to the pathological types, clinical stages, and metastasis of the malignant neoplasms of ovary and the patients who have positive expression of VEGF mRNA and bFGF mRNA might have a poor prognosis.

Details

Language :
Chinese
ISSN :
1000-5625
Volume :
25
Issue :
4
Database :
MEDLINE
Journal :
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University
Publication Type :
Academic Journal
Accession number :
12206019