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[Vomiting as a first neurological sign of brain tumors in children].

Authors :
Bos RF
Ramaker C
van Ouwerkerk WJ
Linssen WH
Wolf BH
Source :
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2002 Jul 27; Vol. 146 (30), pp. 1393-8.
Publication Year :
2002

Abstract

Four children (two boys aged 1.5 and 10 years and two girls aged 2 and 9 years) vomited for one-half to four weeks. In one child, ataxia was later also noted and another tilted his head constantly to the left, but this was initially not alarming. In all four cases CT revealed a brain tumour, for which they were operated. Postoperatively, one child had residual tumour tissue that caused no further problems, in two children the tumour was completely excised with no further symptoms and no recurrence in the following 2 years, and in one child complete excision was not possible so that chemotherapy and radiotherapy were given, but metastases nevertheless developed 10 months later and the child died. Vomiting is common in children and in most cases the result of infectious or gastrointestinal causes. Intracranial pathology also can cause vomiting, both by increased intracranial pressure and by direct stimulation of the vomiting centre in the brainstem. Brain tumours in children often lack specific neurological signs in their clinical presentation. Intractable or chronic vomiting without nausea or deregulation of the water and electrolyte balance could therefore indicate the presence of an intracranial process, even when other neurological signs are absent.

Details

Language :
Dutch; Flemish
ISSN :
0028-2162
Volume :
146
Issue :
30
Database :
MEDLINE
Journal :
Nederlands tijdschrift voor geneeskunde
Publication Type :
Academic Journal
Accession number :
12174430