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Antimicrobial diterpenes from the stem bark of Mitrephora celebica.
- Source :
-
Fitoterapia [Fitoterapia] 2002 Aug; Vol. 73 (5), pp. 434-8. - Publication Year :
- 2002
-
Abstract
- Four diterpenes were isolated from the stem bark of Mitrephora celebica through bioassay-guided fractionation. Ent-trachyloban-19-oic acid (1) and ent-kaur-16-en-19-oic acid (2) were identified as the compounds responsible for the antimicrobial activity of the plant against methicillin-resistant Staphylococcus aureus and Mycobacterium smegmatis. 8(14),15-pimaradien-18-oic acid (3) and 7,15-pimaradien-18-oic acid (4) were isolated from the same fraction and were inactive against the microorganisms.
Details
- Language :
- English
- ISSN :
- 0367-326X
- Volume :
- 73
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Fitoterapia
- Publication Type :
- Academic Journal
- Accession number :
- 12165345
- Full Text :
- https://doi.org/10.1016/s0367-326x(02)00124-7