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[Genetics of lymphedema: from Milroy's disease to cancer investigations].
- Source :
-
La Revue de medecine interne [Rev Med Interne] 2002 Jun; Vol. 23 Suppl 3, pp. 379s-387s. - Publication Year :
- 2002
-
Abstract
- New insight has recently been obtained into the molecular mechanisms regulating lymphatic development and function during embryogenesis. VEGF-C and D ligands have been shown to stimulate lymphangiogenesis and their lymphatic-specific receptor VEGFR-3 is linked to the human congenital and hereditary lymphedema in humans. Above all, new focus on lymphatic endothelial cells gives opportunities for developing innovative therapies for lymphedema and cancer metastasis.
Details
- Language :
- French
- ISSN :
- 0248-8663
- Volume :
- 23 Suppl 3
- Database :
- MEDLINE
- Journal :
- La Revue de medecine interne
- Publication Type :
- Academic Journal
- Accession number :
- 12162200
- Full Text :
- https://doi.org/10.1016/s0248-8663(02)80379-4