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Type 2 diabetes mellitus in children: prenatal and early infancy risk factors among native canadians.
- Source :
-
Archives of pediatrics & adolescent medicine [Arch Pediatr Adolesc Med] 2002 Jul; Vol. 156 (7), pp. 651-5. - Publication Year :
- 2002
-
Abstract
- Background: Type 2 diabetes mellitus is increasingly being observed among children and youth, including the Native population of Canada. Only one study has investigated prenatal and early infancy risk factors for the disease.<br />Methods: A case-control study was conducted; 46 patients younger than 18 years were recruited from the only clinical center for the treatment of diabetes serving the province of Manitoba, and 92 age- and sex-matched controls were recruited from a pediatric ambulatory clinic serving a large Native population in Winnipeg, Manitoba. Information on exposure to prenatal and early infancy risk factors was obtained through questionnaires administered by a Native nurse-interviewer.<br />Results: Multiple logistic regression modeling identified preexisting diabetes (odds ratio [OR], 14.4; 95% confidence interval [CI], 2.86-72.5), gestational diabetes (OR, 4.40; 95% CI, 1.38-14.1), and breastfeeding longer than 12 months (OR, 0.24; 95% CI, 0.13-0.99) as significant independent predictors of diabetic status. Other factors, such as low (<2500 g) and high (>4000 g) birth weight and maternal obesity, were also associated with diabetes in our population, but the elevated risks were not statistically significant.<br />Conclusion: Breastfeeding reduces the risk of type 2 diabetes among Native Canadian children and should be promoted as a potential intervention to control the disease.
- Subjects :
- Adolescent
Breast Feeding ethnology
Case-Control Studies
Child
Child Development
Child, Preschool
Diabetes Mellitus, Type 2 prevention & control
Female
Health Promotion
Humans
Infant
Infant, Newborn
Logistic Models
Male
Manitoba epidemiology
Manitoba ethnology
Odds Ratio
Pregnancy
Pregnancy Complications epidemiology
Pregnancy Complications ethnology
Prenatal Care methods
Risk Factors
Surveys and Questionnaires
Diabetes Mellitus, Type 2 ethnology
Diabetes Mellitus, Type 2 etiology
Indians, North American
Maternal Behavior ethnology
Prenatal Care standards
Subjects
Details
- Language :
- English
- ISSN :
- 1072-4710
- Volume :
- 156
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Archives of pediatrics & adolescent medicine
- Publication Type :
- Academic Journal
- Accession number :
- 12090830
- Full Text :
- https://doi.org/10.1001/archpedi.156.7.651