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[Hyperbaric subarachnoid ropivacaine in ambulatory surgery: comparative study with hyperbaric bupivacaine].
- Source :
-
Revista espanola de anestesiologia y reanimacion [Rev Esp Anestesiol Reanim] 2002 Feb; Vol. 49 (2), pp. 71-5. - Publication Year :
- 2002
-
Abstract
- Objectives: To compare the clinical efficacy of hyperbaric 0.5% ropivacaine and 0.5% bupivacaine in subarachnoid blockade for ambulatory surgery.<br />Material and Method: Randomized double-blind study of 90 patients undergoing lower abdominal surgery. Subarachnoid blockade was achieved with 0.5% ropivacaine (12.5 mg) or 0.5% bupivacaine (12.5 mg) in 10% glucose. We recorded age, sex, weight, latency, extension of motor and sensory blocks, duration of surgery, side effects and quality as perceived by the surgeon and the patient.<br />Results: The two groups were similar with respect to latency time and extension of sensory block. Durations of motor (68.9 +/- 22.9 min) and sensory (127.0 +/- 24.3 min) blocks were significantly shorter with ropivacaine than with bupivacaine (133.3 +/- 29.4 and 174.9 +/- 25.5 min, respectively). Patients in the ropivacaine group also experienced a less intense motor block (Bromage 1, 11.1% vs. 93.3%) and fewer episodes of hypotension 0% vs. 17.7%) or bradycardia (4.4% vs. 8.8%) than those in the bupivacaine group. No neurotoxic effects or instances of postdural puncture headache were recorded.<br />Conclusions: Hyperbaric 0.5% ropivacaine offers certain advantages over hyperbaric 0.5% bupivacaine for subarachnoid block in outpatient surgery. Duration and intensity of the sensory-motor blockade is less with ropivacaine and fewer cardiovascular side effects develop.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Amides adverse effects
Amides pharmacology
Anesthesia Recovery Period
Anesthetics, Local adverse effects
Anesthetics, Local pharmacology
Bradycardia chemically induced
Bupivacaine adverse effects
Bupivacaine pharmacology
Double-Blind Method
Female
Hemodynamics drug effects
Humans
Hypotension chemically induced
Male
Middle Aged
Neuromuscular Blockade
Patient Acceptance of Health Care
Pressure
Ropivacaine
Subarachnoid Space
Ambulatory Surgical Procedures
Amides administration & dosage
Anesthesia, Spinal
Anesthetics, Local administration & dosage
Bupivacaine administration & dosage
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0034-9356
- Volume :
- 49
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Revista espanola de anestesiologia y reanimacion
- Publication Type :
- Academic Journal
- Accession number :
- 12025250