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Thyroid uptake and scintigraphy using 99mTc pertechnetate: standardization in normal individuals.

Authors :
Ramos CD
Zantut Wittmann DE
Etchebehere EC
Tambascia MA
Silva CA
Camargo EE
Source :
Sao Paulo medical journal = Revista paulista de medicina [Sao Paulo Med J] 2002 Mar 07; Vol. 120 (2), pp. 45-8.
Publication Year :
2002

Abstract

Context: Thyroid uptake and scintigraphy using 99mTc-pertechnetate has proven to be more advantageous than with 131I-iodide, since the images have better quality, the procedure is faster and the patient is submitted to a lower radiation dose.<br />Objective: The purpose of this study was to standardize a simple and fast methodology for performing thyroid uptake and scintigraphy and to determine the normal values for 99mTc- pertechnetate uptake.<br />Type of Study: Prospective, non-randomized.<br />Setting: Division of Nuclear Medicine, Department of Radiology, School of Medical Sciences, Campinas State University.<br />Participants: The study consisted of 47 normal individuals, 30 women and 17 men, with ages ranging from 19 to 61 years (mean of 33 years).<br />Procedures: The laboratory assessment of thyroid function consisted of serum dosages of ultra-sensitive thyroxin and thyrotrophin. Twenty minutes after an intravenous injection of 10 mCi (370 MBq) of 99mTc-pertechnetate, the images were obtained on a computerized scintillation camera equipped with a low-energy high-resolution parallel hole collimator.<br />Results: All the individuals were euthyroid both on clinical and laboratory evaluation. The baseline thyroid 99mTc-pertechnetate uptake ranged from 0.4 to 1.7%. The uptake values obtained in these normal individuals showed that 95% presented a thyroid uptake that ranged from 0.4 to 1.5% of the injected dose.<br />Conclusion: The assessment of thyroid structure and function using 99mTc-pertechnetate is a simple, fast and efficient method, which could easily become a part of the routine studies in nuclear medicine laboratories.

Details

Language :
English
ISSN :
1516-3180
Volume :
120
Issue :
2
Database :
MEDLINE
Journal :
Sao Paulo medical journal = Revista paulista de medicina
Publication Type :
Academic Journal
Accession number :
11994772
Full Text :
https://doi.org/10.1590/s1516-31802002000200004