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Disseminated Cladophialophora bantiana infection in a heart transplant recipient.
- Source :
-
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [J Heart Lung Transplant] 2002 Apr; Vol. 21 (4), pp. 503-5. - Publication Year :
- 2002
-
Abstract
- Cerebral phaeohyphomycosis caused by Cladophialophora bantiana, a dematiaceous fungus, is a rare disease. The majority of cases have been reported among immunocompetent patients; only 4 cases have been published that describe transplantation patients. The overall prognosis is poor. Surgical therapy in combination with chemotherapy with itraconazole is recommended. We report the case of a heart transplant recipient with cutaneous, cerebral, and lung manifestation of Cladophialophora bantiana who died despite surgical and systemic, high-dosage itraconazole treatment.
- Subjects :
- Antifungal Agents therapeutic use
Autopsy
Central Nervous System Fungal Infections drug therapy
Central Nervous System Fungal Infections mortality
Cerebellum microbiology
Fatal Outcome
Humans
Itraconazole therapeutic use
Kidney microbiology
Liver microbiology
Lung microbiology
Magnetic Resonance Imaging
Male
Middle Aged
Surgical Wound Infection drug therapy
Surgical Wound Infection mortality
Central Nervous System Fungal Infections etiology
Cladosporium
Heart Transplantation
Phialophora
Surgical Wound Infection etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1053-2498
- Volume :
- 21
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 11927230
- Full Text :
- https://doi.org/10.1016/s1053-2498(01)00357-6