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[Peritoneal fluid and plasma 4-hydroxynonenal and malonyldialdehyde concentrations in infertile women].
- Source :
-
Ginekologia polska [Ginekol Pol] 2001 Dec; Vol. 72 (12A), pp. 1316-20. - Publication Year :
- 2001
-
Abstract
- Objectives: To investigate the possible role of oxidative stress in the pathogenesis of female infertility, we examined the peritoneal fluid (PF) and plasma lipid peroxides levels in infertile women.<br />Materials and Methods: 4-hydroxynonenal (4-HNE) and malonyldialdehyde (MDA) concentrations were measured in peritoneal fluid and plasma samples obtained from: 10 infertile women with minimal and mild endometriosis, 24 patients with unexplained infertility, 11 women with PCOS and 14 patients with tubal infertility.<br />Results: PF lipid peroxides level was significantly higher in women with idiopathic infertility compared to other groups. Plasma 4-HNE and MDA concentrations did not differ significantly between the infertile groups. No significant difference or relationship was observed between peritoneal fluid and plasma lipid peroxides levels.<br />Conclusions: Increased free radicals activity in the peritoneal fluid environment may be the factor responsible for some cases of "unexplained infertility".
Details
- Language :
- Polish
- ISSN :
- 0017-0011
- Volume :
- 72
- Issue :
- 12A
- Database :
- MEDLINE
- Journal :
- Ginekologia polska
- Publication Type :
- Academic Journal
- Accession number :
- 11883271