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Antibiotic-resistant gram-negative organisms in pediatric chronic-care facilities.
- Source :
-
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2002 Mar 15; Vol. 34 (6), pp. 760-6. Date of Electronic Publication: 2002 Feb 07. - Publication Year :
- 2002
-
Abstract
- This study was designed to define the prevalence of colonization with antibiotic-resistant gram-negative rectal specimens were obtained from subjects residing in 2 pediatric extended-care facilities and were processed to identify gram-negative organisms resistant to ceftazidime, gentamicin, meropenem, and piperacillin-tazobactam. Horizontal transmission was assessed by analyzing all resistant isolates by pulsed-field gel electrophoresis. Forty percent of subjects were colonized with >/=1 resistant bacillus; >60% of organisms were resistant to >/=2 of the antibiotics tested. Colonization was disproportionate among residents with a tracheostomy or other prosthesis. More than 65% of colonized subjects shared 1 organism with another resident, with cross-colonization occurring among both enteric and nonenteric species. Children residing in chronic-care facilities represent a large reservoir for resistant bacilli. Such colonization may be amenable to simple barrier infection-control procedures.
- Subjects :
- Adolescent
Adult
Child
Child Care
Child, Preschool
Disease Transmission, Infectious
Female
Gram-Negative Bacteria drug effects
Gram-Negative Bacterial Infections epidemiology
Gram-Negative Bacterial Infections transmission
Humans
Male
Risk Factors
Drug Resistance, Bacterial physiology
Gram-Negative Bacteria physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1537-6591
- Volume :
- 34
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- Publication Type :
- Academic Journal
- Accession number :
- 11850860
- Full Text :
- https://doi.org/10.1086/338957