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[Experimental study on effect of qishejingkang recipe on activity of alkaline phosphatases in osteophyte formation of degenerated cervical vertebrae of rabbits].

Authors :
Wang Y
Shi Q
Shen P
Source :
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine [Zhongguo Zhong Xi Yi Jie He Za Zhi] 2000 Mar; Vol. 20 (3), pp. 199-201.
Publication Year :
2000

Abstract

Objective: To study the effect of Qishejingkang recipe (QSJKR) on activity of alkaline phosphatase (ALP) in osteophyte formation of degenerated cervical vertebrae.<br />Methods: A model of degenerated cervical vertebrae in the rabbit was established through resection of the cervical supraspinous and interspinous ligaments from the cervical spine elicited by surgical intervention. The sites of osteophyte was observed with a light microscope. The activity of ALP of the annuls fibrosis and nucleus pulpous, end-plate in each cervical spine was assayed with biochemical method respectively.<br />Results: Osteophyte come from end-plate, the activity of ALP in the degenerated end-plate in QSJKR group declined significantly compared with model group.<br />Conclusion: QSJKR could decrease the activity of ALP in end-plate of degenerated cervical vertebrae and it might inhibit the formation of osteophyte.

Details

Language :
Chinese
ISSN :
1003-5370
Volume :
20
Issue :
3
Database :
MEDLINE
Journal :
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
Publication Type :
Academic Journal
Accession number :
11789285